What Is Ccnd1 at Versekering

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What Is Ccnd1

What Is Ccnd1. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Go to variation viewer for ccnd1 variants.

CCND1 Breakapart
CCND1 Breakapart from www.cytocell-us.com

The human ccnd1 gene is located on the long arm of chromosome 11 (band 11q13). Cyclin d1 is activated in the g1 phase of the cell cycle; The combination of cryptic igh/ccnd1 fusion, acquisition of the ccnd1 3ā€² utr translocation involving 12p in conjunction with biallelic tp53 alterations (deletion and point mutation), and the reported adverse effect of acquired ccnd1 mutations in mcl also explain the negative sox11 expression by the lymphoma cells and may have contributed to.

CCND1 Breakapart

It is 13,388 base pairs long, and translates into 295 amino acids. This gene has a cancer hallmark. Cyclins function as regulators of cdk kinases. Abbreviation is mostly used in categories: